Pentraxins in Complement Activation and Regulation

The complement is the first line of immune defense system involved in elimination of invading pathogens and dying host cells.Its activation is mainly triggered by immune complexes click here or pattern recognition molecules (PRMs) upon recognition against non-self or altered self-cells, such as C1q, collectins, ficolins, and properdin.Recent findin

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Novel Clostridium difficile Anti-Toxin (TcdA and TcdB) Humanized Monoclonal Antibodies Demonstrate In Vitro Neutralization across a Broad Spectrum of Clinical Strains and In Vivo Potency in a Hamster Spore Challenge Model.

Clostridium difficile (C.difficile) infection (CDI) is the main cause of nosocomial antibiotic-associated colitis and increased incidence of community-associated diarrhea in industrialized countries.At present, the primary treatment of CDI is antibiotic administration, which is effective but often associated with recurrence, especially in the elder

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Music Therapy in Global Aphasia: A Case Report

Patients affected by global aphasia are no longer able to understand, produce, name objects, write and read.It occurs as a result of functional damage of ischemic or hemorrhagic origin affecting the entire peri-silvan region and frontal operculum.Rehabilitation training aims to promote an early intervention in the acute phase.We described a case of

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School practices to promote social distancing in K-12 schools: review of influenza pandemic policies and practices

Abstract Background During an evolving influenza pandemic, community mitigation strategies, such as social distancing, can slow down virus transmission in schools and surrounding communities.To date, research on school practices to promote social distancing in primary and secondary schools has focused on prolonged school closure, with little attent

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